DSIP

Peptides

Updated : May 13, 2026

Class: Sleep-Modulating Neuropeptide

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide first isolated from rabbit cerebral
venous blood. It plays a key role in regulating sleep architecture — specifically promoting delta (deep) sleep
— as well as modulating stress responses, cortisol, and the hypothalamic-pituitary axis. It has demonstrated
anxiolytic, analgesic, and adaptogenic properties with a favorable safety profile.

Key Benefits

• Promotes deep delta-wave sleep and normalizes sleep architecture
• Reduces cortisol and modulates the stress response
• Anxiolytic effects — reduces anxiety without sedation
• Analgesic properties — may reduce chronic pain perception
• Adaptogenic — helps normalize disrupted biological rhythms

Standard Dosage Scheduled

Parameter

Details

Dose

100–500 mcg subcutaneous injection

Frequency

Once daily, 30–60 minutes before sleep

Cycle

1–2 week courses; repeat as needed

Note

Short courses are preferred; effects on sleep often felt immediately

Stack

Complements Selank or Semax for comprehensive neuro support

DSIP

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